Amplitube 5.0.1 is not working properly in Reaper.
Overall version 5 loads MUCH slower than version 4 which I really hope is addressed.
Besides that, it will crash the DAW when the preset system in Reaper is used either by selecting a preset or by using FX Chains.
Can anyone else test this and confirm you're seeing the issue as well?
Details below...
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Steps to repeat:
Load blank Reaper session (latest version 6.19) on Windows 10 Pro 64bit (latest version 20H2)
Create track
Add VST3 (or VST2) version of Amplitube 5
It will load too slowly but it should load and then choose any amp other than default
Save as a preset in Reaper's built in preset manager (click the + icon in the bar above the plugin GUI next to Param)
Click 'Save preset' and give it any name
Delete Amplitube plugin from track
Record arm the track (or have the session playing back)
Add Amplitube plugin to track
It will crash/hang the DAW
Temporary fix:
Delete all presets for the plugin in Reaper preset manager
Another situation:
Load blank Reaper session (latest version 6.19)
Create track
Add VST3 (or VST2) version of Amplitube 5
It will load too slowly but it should load and then choose any amp other than default
Use the Reaper plugin window and choose FX > Save FX Chain
Give it any name and save
Delete Amplitube plugin from track
Record arm track or hit play
Go back to FX > Add FX chain and select the chain that you just saved
It will hang/crash the DAW
Conclusion: Amplitube 5 does not respond correctly to the Reaper preset when track is record armed or playing back.
It will crash/hang the DAW. Amplitube 4 does respond properly to this behavior and works much faster.