Hello and welcome to the forum.
I am sorry to hear about the problems you are running into.
For the first issue you'll need to turn down Direct Monitoring on the AXE I/O.
User Manual, page 6 wrote:14. MONITOR- the Monitor knob allows you to blend your input signals with the playback streams from your computer. This allows you to monitor your input signal with zero latency. If the knob is positioned at 12 o’clock, the input signal and the playback stream will be equally balanced. Turning the knob to the left will increase the level of the direct signal; turning to the right will increase the level of the playback stream from the DAW. This control works both for Outputs 1-2 and Headphones.
Second issue: that's a Microsoft redistribute run-time library. I do not know whether the software installer installs it or just expects it the be already there.
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As this is primarily a user to user forum, someone-else may chime in [#]. Meanwhile, the best thing to do is
check the FAQs, via here. If they do not resolve the issue, there is a link at the top to the Technical Support form, for some one to one investigation and help. Response time is usually within 2 working days (US (East Coast) Business hours, generally), but in the current circumstances please allow some more time.
[#] But please remember that the same symptoms do not necessarily mean the same problem.
And, to help others who run into a similar problem, please let us know what you did to resolve the problem, but without directly quoting any correspondence from Support.
